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Molecular Mass Spectrometry Facility MMSF
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  3. Dr. Yongxuan Su

Yongxuan Su, Ph.D.

Research and Development Engineer 4

  • Ph.D. (1998) in Analytical Chemistry, Xiamen University, CHINA
  • B.S. (1994) in Chemistry, Xiamen University, CHINA
  • Research and Development Engineer 4 (2017-present); Senior Development Engineer (2005-2016); Development Engineer (2004-2005): Department of Chemistry and Biochemistry, UCSD.
  • Postdoc (2001-2004): Department of Chemistry and Biochemistry, UCSD.
  • Postdoc (1999-2001): Chemistry Division, Los Alamos National Laboratory.
  1. Tsai CY., Sun S., Zhang HY., Local A, Su YX., Gross LA., Rice WG., Howell SB. "APTO-253 Is a New Addition to the Repertoire of Drugs that Can Exploit DNA BRCA1/2 Deficiency", Molecular Cancer Therap, 17 (6), 1167-1176 (2018)
  2. Moreno-Ulloa A., Najera-Garcia N., Hernandez M., Ramirez-Sanchez I., Taub PR., Su YX., Beltran-Partida E., Ceballos G., Dugar S., Schreiner G., Best BM., Ciaraldi TP., Henry RR., Villarreal F. "A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints", Food & Function, 9 (1), 307-319 (2018)
  3. Argade S., Berecz Z., Su YX., Parsons CL. "Increased toxic urinary cations in males with interstitial cystitis: a possible cause of bladder symptoms", World J. of Urology, 34 (12), 1685-1691 (2016).
  4. Barnett CF., Moreno-Ulloa A., Shiva S., Ramirez-Sanchez I., Taub PR., Su YX., Ceballos G., Dugar S., Schreinerf G., Villarreal F. "Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers", Food & Function, 6 (3), 824-833 (2015)
  5. Parsons CL., Shaw T., Berecz Z., Su YX., Zupkas P., Argade S. "Role of urinary cations in the aetiology of bladder symptoms and interstitial cystitis", Bju Int. 114 (2), 286-293 (2014)
  6. Ibsen S., Su Y., Norton J., Zahavy E., Hayashi T., Adams S., Wrasidlo W., Esener S. “Extraction protocol and mass spectrometry method for quantification of doxorubicin released locally from prodrugs in tumor tissue”, J. Mass Spec., 48 (7), 768-773, DOI: 10.1002/jms.3221 (2013).
  7. Argade S., Shaw T., Su Y., Parsons C. L. “Tamm-Horsfall protein-associated nucleotides in patients with interstitial cystitis”, BJU Int, 111 (5), 811-819, doi: 10.1111/j.1464-410X.2012.11691.x. (2013).
  8. Ibsen S., Zahavy E., Wrasidlo W., Hayashi T., Norton J., Su Y., Adams S., Esener S. “Localized in vivo activation of a photoactivatable doxorubicin prodrug in deep tumor tissue”, Photochemistry and Photobiology, 89 (3), 698-708, doi: 10.1111/php.12045 (2013).
  9. Charusanti P., Fong N.L., Nagarajan H., Pereira AR, Li H.J., Abate EA, Su Y.X., Gerwick W.H., Palsson B.O. “Exploiting adaptive laboratory evolution of streptomyces clavuligerus for antibiotic discovery and overproduction”, PLOS ONE, 7 (3), e33727. doi:10.1371/journal.pone.0033727 (2012).
  10. Lim SH., Su YX., Cohen SM. “Supramolecular tetrahedra of phosphines and coinage metals”, ANGEW. CHEM.-INTERNATIONAL EDITION , 51 (21), 5106 – 5109 (2012).
  11. Kim M., Cahill JF., Su YX., Prather KA., Cohen SM. “Postsynthetic ligand exchange as a route to functionalization of ‘inert’ metal–organic frameworks”, Chemical Sci, 3 (1), 126 – 130 (2012).
  12. Hatch LE., Creamean JM., Ault AP., Surratt JD., Chan MN., Seinfeld JH., Edgerton ES., Su YX., Prather K.A. "Measurements of isoprene-derived organosulfates in ambient aerosols by aerosol time-of-flight mass spectrometry - Part 2: Temporal variability and formation mechanisms". Environ. Sci. Tech, 45, 8648-8655 (2011).
  13. Anjard C., Su Y.X., Loomis W.F. "The polyketide MPBD initiates the SDF-1 signaling cascade that coordinates terminal differentiation in Dictyostelium", Eukaryotic Cell, 10, 956-963 (2011).
  14. Hatch L.E., Creamean J.M., Ault A.P., Surratt J.D., Chan M.N., Seinfeld J.H., Edgerton E.S., Su Y.X., Prather K.A. "Measurements of isoprene-derived organosulfates in ambient aerosols by aerosol time-of-flight mass spectrometry - Part 1: Single particle atmospheric observations in Atlanta", Environ. Sci. Tech, 45, 5105-5111 (2011).
  15. Pratt K.A., Mayer J.E., Holecek J.C., Moffet R.C., Sanchez R.O., Rebotier T.P., Furutani H., Gonin M., Fuhrer K., Su Y.X.,Guazzotti S., Prather K.A. "Development and characterization of an aircraft aerosol time-of-flight mass spectrometer", Anal. Chem., 81(5), 1792-1800 (2009).
  16. Anjard C., Su Y.X., Loomis W.F. "Steroids initiate a signaling cascade that triggers rapid sporulation in Dictyostelium",Development, 136, 803-812 (2009).
  17. Mühle J., Lueker T.J., Su Y.X., et al. “Trace Gas and Particulate Emissions from the 2003 Southern California Wildfires”,J. Geophys. Res-Atmos,112(D3), D03307 (2007).
  18. Su YX., Sipin MF., Spencer MT., et al. “Real-time Characterization of the Composition of Individual Particles Emitted from Ultrafine Particle Concentrators”, Aerosol Sci. Tech, 40 (6), 437-455 (2006).
  19. Su YX., Sipin M.F., Prather K.A., et al. “ATOFMS characterization of individual model aerosol particles used for exposure studies”, Aerosol Sci. Tech, 39(5), 400-407 (2005).
  20. Su YX., Sipin M.F., Furutani H., and Prather K.A. “Development and characterization of an aerosol time-of-flight mass spectrometer with increased detection efficiency”, Anal. Chem, 76, 712 (2004).
  21. Su YX., Jin, Z., and Duan YX. “Analytical characteristics of microwave plasma time-of-flight mass spectrometry with alternative/mixed gases and "off-cone" sampling”, Canadian J. Anal. Sci. and Spectros, 48(3), 163 (2003).
  22. Duan YX., Su YX., Jin, Z. “Capillary-discharge-based portable detector for chemical vapor monitoring”, Rev. of Scientific Inst, 74 (5), 2811 (2003).
  23. Su YX., Jin Z., Duan YX. “Mapping the ion kinetic energy in a helium microwave plasma orthogonal acceleration time-of-flight mass spectrometer”, J. Mass Spectrom, 36, 1156 (2001).
  24. Jin Z., Su YX., Duan Y.X. “A low-power, atmospheric pressure, pulsed plasma source for molecular emission spectrometry”, Anal. Chem, 73, 360 (2001).
  25. Jin, Z., Su YX., Duan YX. “Development of a polyaniline-based optical ammonia sensor”, Sensors and Actuators B-Chemical, 72 (1), 75 (2001).
  26. Jin, Z., Su YX., Duan YX. “A novel method for polyaniline synthesis with immobilized horseradish peroxidase enzyme”, Synthtic  Metal, 122 (2), 237-242 (2001).
  27. Duan YX., Su YX., Jin Z et al., "Measurements of calcium isotopes and isotope ratios: a new method based on helium plasma source "off-cone" sampling time-of-flight mass spectrometry", J. Anal. At. Spectrom, 16 (7), 756-761 (2001). 
  28. Jin, Z., Su YX., Duan YX, "An improved optical pH sensor based on polyaniline", Sensors and Actuators B-Chemical, 71 (1-2), 118-122 (2000).
  29. Su YX., Jin Z., Duan YX. “Helium plasma source time-of-flight mass spectrometry: Off-cone sampling for elemental analysis”, Anal. Chem, 72, 2455 (2000).
  30. Su YX., Duan YX., Jin Z. “Development and evaluation of a glow discharge microwave-induced-plasma tandem source for time-of-flight mass spectrometry”, Anal. Chem, 72, 5600 (2000).
  31. Su YX., Jin Z., Duan YX., Koby M., Majidi V., Olivares JA., Abeln SP. “Highly sensitive beryllium detection with microwave plasma source optical emission spectrometry”, Anal. Chim. Acta, 422, 209 (2000).
  32. Duan YX., Su YX., Jin Z., Abeln SP. “A field portable plasma source monitor for real-time air particulate monitoring”, Anal. Chem, 72, 1672 (2000).
  33. Duan YX., Su YX., Jin Z., Abeln SP. "Design and development of a highly sensitive, field portable plasma source instrument for on-line liquid stream monitoring and real-time sample analysis", Rev. of Scientific Inst, 71 (3), 1557-1563 (2000).
  34. Duan YX., Su YX., Jin Z. "A new, simple, compact GD-MIP tandem ion source for elemental time-of-flight mass spectrometry", J. Anal. At. Spectrom, 15 (10), 1289-1291 (2000).
  35. Su YX., Yang PY., Zhou Z., Wang XR., Li FM., Huang BL., Ren JS., Chen M., Ma HB., Zhang GS. "Feasibility of applying microsecond-pulse glow discharge time of flight mass spectrometry in surface depth analysis", Spectrochim. Acta, 53B, 1413-1420 (1998).
  36. Su YX., Yang PY., Zhou Z., Li FM., Wang XR., Huang BL. "Suppression of gas species signals in direct current glow discharge time-of-flight mass spectrometry", J. Anal. At. Spectrom, 13, 1271-1275 (1998).
  37. Su YX., Zhou Z., Yang PY., Wang XR., Huang BL. "Study of a pulsed glow discharge ion source for time-of-flight mass spectrometry", Spectrochim. Acta, 52B, 633-641 (1997).
  38. Su YX., Yang PY., Chen DY., et. al., "Microwave-induced plasma boosted microsecond-pulse glow discharge optical emission spectrometry", J. Anal. At. Spectrom, 12 (8), 817-822 (1997).
  39. Yang PY., Su YX., Zhou Z., et al., "Analytical performance of a microsecond-pulse glow discharge time of flight mass spectrometer", Anal. Sci, 13 (S, Supplement), 3-6 (1997).
  40. Hang W., Yang PY., Wang XR., Yang CL., Su YX., Huang BL, " Microsecond pulsed glow discharge time of flight mass spectrometer", Rapid Comm. in Mass Spec, 8 (8), 590-594 (1994).